Аortic arch atheroma as a source of arterio-arterial embolism and ischemic stroke

Introduction. Currently, despite the introduction of modern diagnostic algorithms in 20-40 % patients with ischemic stroke, it is not possible to establish its cause. Potential causes acute cerebral ischemia cryptogenic stroke include paroxysmal atrial fibrillation, patent foramen ovale, cardiomyopathy, carotid network, aortic arch atheroma, and cancer-associated thrombophilia. Target : systematize data on methods for diagnosing preventing atheroma. Material . The literature search was carried out electronic systems Scopus, eLibrary, PubMed using key words: pathogenesis stroke. Results At present, such a detailed study therapeutic strategies prevention recurrent thrombotic events none drugs has proven advantage. Although NAVIGATE ESUS RESPECT trials did show superiority oral anticoagulants over antiplatelet agents strokes found that heterogeneous, which requires differentiated approach secondary prevention. Conclusion Аortic atheroma can be cause embolic syndrome main are transesophageal echocardiography computed tomographic angiography. strategy treatment lipid-lowering, antithrombotic therapy combination blockers renin-angiotensin-aldosterone system.